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PAS 1
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Results showed that the drug has significant dose-dependent anti-ovulatory property and was more effective when administered before proestrus. The oestrus cycle especially the dia-oestrous phase was significantly prolonged. Thus, CBE treatment significantly altered natural ovulation times. However there was resumption of normal oestrus cycle 10 days after stopping the administration of CBE. Our results suggest that CBE altered the pattern of oestrogen secretion/levels, and this led to delayed luteolysis. [Mcneil, R.t & Noronha, C.c & Kusemiju, T.o & Okanlawon, Abayomi. (2003). The Anti-ovulatory Effect of a Seed Extract of Ricinus Communis-linn. Nigerian Journal of Health and Biomedical Sciences. 2. 10.4314/njhbs.v2i1.11455.] https://www.researchgate.net/publication/272451423_The_Anti-ovulatory_Effect_of_a_Seed_Extract_of_Ricinus_Communis-linn/
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PAS 2
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Amongst all, the species Ricinus communis or castor plant has high traditional and modern medicinal values. The individual parts of the plant like the seed, seed oil, leaves and the roots showed their importance in pharmacology. Traditionally, the plant has been used for the treatment of various diseases in traditional or folk remedies throughout the world. In modern pharmacology, this plant is reported to possess antioxidant, anti-inflammatory, anti-diabetic, central analgesic, antitumor, anti-nociceptive, antiasthmatic activity and other medicinal properties. These activities of the plant are due to the presence of important phytochemical constituents like flavonoids, glycosides, alkaloids, steroids, terpenoids etc. The aim of present article is to explore the chemical constituents, their structures and medicinal importance of Ricinus communis. [Singh, Ram & ., Geetanjali. (2015). Phytochemical and Pharmacological Investigations of Ricinus communis Linn.. Algerian J. Nat. Products. 3. 120-129.] https://www.researchgate.net/publication/271079059_Phytochemical_and_Pharmacological_Investigations_of_Ricinus_communis_Linn
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PAS 3
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Anti-Implantation activity: The ether soluble portion of the methanol extract of Ricinus communis var. minor possesses anti-implantation, anticonceptive and estrogenic activity in adult female rats and rabbits when administered subcutaneously at a dose upto 1.2g/kg and 600mg/kg respectively in divided doses. [Manpreet Rana et al /Int.J.PharmTech Res.2012,4(4)] http://sphinxsai.com/2012/oct-dec/Pharmpdf/PT=48(1706-1711)OD12.pdf
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PAS 4
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The anti-fertility effects of R. communis were studied in male rats which revealed a reduction of epididymal sperm counts. Main features observed after treatment with 50% ethanolic extracts of R. communis include alteration in motility and morphology of sperms was also affected. In another study, semen parameters have been observed wherein the suppression of testicular function is reported in male Wistar rats treated with R. communis (10 mg/kg). Clinical study, carried out by Isichei and colleagues, for antifertility effects in females with a single dose have prevented pregnancy for 12 months [Abdul WM, Hajrah NH, Sabir JS, Al-Garni SM, Sabir MJ, Kabli SA, Saini KS, Bora RS. Therapeutic role of Ricinus communis L. and its bioactive compounds in disease prevention and treatment. Asian Pac J Trop Med [serial online] 2018 [cited 2020 Sep 8]; 11:177-85. Available from: http://www.apjtm.org/text.asp?2018/11/3/177/228431]
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Agro Ecological Zone
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Western plain, kachchh and part of kathiawar peninsula, hot arid eco-region (2.3) ,Coastal Plains and Hills (XIII),Bhal and Coastal area (GJ-8) 14.26% North Gujarat ( GJ-4) 19.87% North west zone (GJ-5) 36.38 North Saurashtra (GJ-6) 29.49
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Community Practices
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Control of anestrous in buffaloes through locally available resources [R. Kumar, R. Singh & R. Rajkumar (2007) Control of anestrous in buffaloes through locally available resources, Italian Journal of Animal Science, 6:sup2, 659-662, DOI: 10.4081/ijas.2007.s2.659] https://www.tandfonline.com/doi/pdf/10.4081/ijas.2007.s2.659
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Practice ID
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DTP0010000000097
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Annotation ID
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GIAN/GAVL/1780
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Reference
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HBN database
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Disease
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Repeat Breeding
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Disease Description
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A repeat breeder cow is defined as one that, • Has experienced three or more unsuccessful services. • Have normal estrous cycles with approximately 21 days intervals. • Is free from palpable abnormalities. • Shows no abnormal vaginal discharges. • Has calved at least once before. • Is less than 10 years old.
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Management Practices
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In the recent decade, uterine lavage with normal saline and hypertonic dextrose (50%) solution gain popularity and advocacy. In repeat breeding cows with endometritis, infusion of 300-400 ml of isotonic saline into the uterus claimed to have advantage of good cellular response. Some studies describe the use of hypertonic dextrose also. Infusion of ozone into the uterus is a new treatment option in uterine infections. Antiseptics do not create the issue of milk residues; but many are irritants; previously, iodine preparations like polyvinyl pyrrolidone (Povidone®) were used for the treatment of uterine infections in cattle. But in recent reports, it was noted that the irritant nature of iodine preparations potentially damage the endometrium and reduced the conception rate in forthcoming estrum. Many studies support this view of replacing the antiseptics with intrauterine antibiotic preparations.
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Technology Transfer Terms
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Licensing / Technical Support / Consultancy / Turn Key Project:
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